Antigen presentation: Presenting a newly charged antigen

Antigen-Presenting Cells and Antigen Presentation in Tertiary Lymphoid Organs

Tertiary lymphoid organs (TLOs) form in territorialized niches of peripheral tissues characterized by the presence of antigens; however, little is known about mechanism(s) of antigen handling by ectopic lymphoid structures. In this mini review, we will discuss the role of antigen-presenting cells and mechanisms of antigen presentation in TLOs, summarizing what is currently known about this face...

Antigen presentation

The immune response to infection depends centrally on the T lymphocytes of the immune system, and the detection of infection by T lymphocytes depends in turn on the presentation of antigen to the T cells by molecules encoded in the major histocompatibility complex (MHC). The biological function of these molecules is to bind proteolytic fragments (peptides) derived from foreign proteins generate...

APC Antigen - presenting cell

Det blir allt vanligare att man använder kroppsfrämmande material i dagens sjukvård. Materialen, som kan utgöra allt ifrån slangar, dialysmembran, katetrar, blodpumpar och proteser m.m., används för att bota patienter eller för att minska symptomen från olika typer av sjukdomar. Dessa typer av kroppsfrämmande material kallas för biomaterial eftersom de är avsedda att komma i kontakt med biologi...

Induction of peripheral T cell tolerance by antigen-presenting B cells. II. Chronic antigen presentation overrules antigen-presenting B cell activation.

Ag presentation in the absence of danger signals and Ag persistence are the inductive processes of peripheral T cell tolerization proposed so far. Nevertheless, it has never been definitively shown that chronic Ag presentation per se can induce T cell tolerance independent of the state of activation of APCs. In the present work, we investigated whether chronic Ag presentation by either resting ...

la Antigen Mediated Specific Antigen Presenting Function of Articular Chondrocytes